Tuesday, November 20, 2018

NIAID Scientists Find Evidence of Prions in Eyes of CJD Patients

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Tuesday, Nov. 20, 2018

NIAID Scientists Find Evidence of Prions in Eyes of CJD Patients

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NIAID scientists and their colleagues have found evidence of the infectious agent of sporadic Creutzfeldt-Jakob disease (CJD) in the eyes of deceased CJD patients. The finding suggests that the eye may be a source for early CJD diagnosis and raises questions about the safety of routine eye exams and corneal transplants. Sporadic CJD, a fatal neurodegenerative prion disease of humans, is untreatable and difficult to diagnose. Scientists hope that early diagnosis of prion and related diseases could lead to effective treatments that slow or prevent their spread. About 40 percent of sporadic CJD patients develop eye problems that could lead to an eye exam, meaning the potential exists for the contamination of eye exam equipment designed for repeat use.

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