Thursday, January 17, 2019

NIAID Now: Scientists Reveal How a “Closed” Protein Structure Helps HIV Dodge Antibodies

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Thursday, January 17, 2019

NIAID Now: Scientists Reveal How a "Closed" Protein Structure Helps HIV Dodge Antibodies

HIV-infected cell with "Sorry We're Closed" sign

HIV is a master of sneaking past our natural defenses. Typically, when the body encounters a harmful virus, immune cells recognize viral proteins and stimulate the production of protective proteins called antibodies. HIV, however, has evolved several ways to cloak vulnerable areas of viral proteins. A report released last month from NIAID scientists in the journal MBio reveals new insights into one such tactic of immune invisibility.

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