Wednesday, March 6, 2019

Open-Access Papers About NIAID-Supported Studies

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The NIAID Radiation/Nuclear Countermeasures Program (RNCP) supports extramural research to develop safe and effective radiation medical countermeasures and biodosimetry methods and/or devices for clinical use under emergency situations.

The April 2019 issue of Health Physics has been published and features studies funded by NIAID. The issue includes the following articles describing biomarkers of radiation injury from long-term studies in mouse and non-human primates, as well as papers describing the delayed effects of acute radiation exposure in rodents (best viewed in Chrome): 

COMMENTARY

453

ARS, DEARE, and Multiple-organ Injury: A Strategic and Tactical Approach to Link Radiation Effects, Animal Models, Medical Countermeasures, and Biomarker Development to Predict Clinical Outcome

Thomas J. MacVittie; Ann M. Farese; Maureen A. Kane

 

 

 

BIOMARKERS: A MULTIDISCIPLINARY APPROACH: PAPERS

454–472

Characterizing the Natural History of Acute Radiation Syndrome of the Gastrointestinal Tract: Combining High Mass and Spatial Resolution Using MALDI-FTICR-MSI

Claire L. Carter; Kim G. Hankey; Catherine Booth; Gregory L. Tudor; George A. Parker; Jace W. Jones; Ann M. Farese; Thomas J. MacVittie; Maureen A. Kane

 

 
 

473–483

Targeted Metabolomics Reveals Metabolomic Signatures Correlating Gastrointestinal Tissue to Plasma in a Mouse Total-body Irradiation Model

Jace W. Jones; Zachary Clifford; Fei Li; Gregory L. Tudor; Ann M. Farese; Catherine Booth; Thomas J. MacVittie; Maureen A. Kane

 

 
 

484–502

Effect of Sex on Biomarker Response in a Mouse Model of the Hematopoietic Acute Radiation Syndrome

Jace W. Jones; Jenna Alloush; Rajendran Sellamuthu; Hui Lin Chua; Thomas J. MacVittie; Christie M. Orschell; Maureen A. Kane

 

 
 

503–515

Acute Proteomic Changes in the Lung After WTLI in a Mouse Model: Identification of Potential Initiating Events for Delayed Effects of Acute Radiation Exposure

Weiliang Huang; Jianshi Yu; Jace W. Jones; Claire L. Carter; I. Lauren Jackson; Zeljko Vujaskovic; Thomas J. MacVittie; Maureen A. Kane

 

 
 

516–528

Proteomic Evaluation of the Acute Radiation Syndrome of the Gastrointestinal Tract in a Murine Total-body Irradiation Model

Weiliang Huang; Jianshi Yu; Jace W. Jones; Claire L. Carter; Keely Pierzchalski; Gregory Tudor; Catherine Booth; Thomas J. MacVittie; Maureen A. Kane

 

 

MURINE MODELS OF MULTIPLE-ORGAN INJURY: PAPERS

529–545

Delayed Effects of Acute Radiation Exposure (Deare) in Juvenile and Old Rats: Mitigation by Lisinopril

Meetha Medhora; Feng Gao; Tracy Gasperetti; Jayashree Narayanan; Abdul Hye Khan; Elizabeth R. Jacobs; Brian L. Fish

 

 
 

546–557

Lifelong Residual bone Marrow Damage in Murine Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS): A Compilation of Studies Comprising the Indiana University Experience

Hui Lin Chua; P. Artur Plett; Alexa Fisher; Carol H. Sampson; Sasidhar Vemula; Hailin Feng; Rajendran Sellamuthu; Tong Wu; Thomas J. MacVittie; Christie M. Orschell

 

 

MURINE MODELS OF MULTIPLE-ORGAN INJURY: NOTES

558–565

Cardiac Remodeling and Reversible Pulmonary Hypertension During Pneumonitis in Rats after 13-Gy Partial-Body Irradiation with Minimal Bone Marrow Sparing: Effect of Lisinopril

Elizabeth R. Jacobs; Jayashree Narayanan; Brian L. Fish; Feng Gao; Leanne M. Harmann; Carmen Bergom; Tracy Gasperetti; Jennifer L. Strande; Meetha Medhora

 

 
 

566–570

Effects of Diet on Late Radiation Injuries in Rats

John E. Moulder; Brian L. Fish; Eric P. Cohen; Jessica B. Flowers; Meetha Medhora

 
 
 

Visit the NIAID website to learn more about the Radiation and Nuclear Countermeasures Program.

 


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