Thursday, May 16, 2019

Human Antibody Reveals Hidden Vulnerability in Influenza Virus

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Thursday, May 16, 2019

Human Antibody Reveals Hidden Vulnerability in Influenza Virus

Flu virus particles

The ever-changing "head" of an influenza virus protein has an unexpected Achilles heel, report scientists funded by NIAID. The team discovered and characterized the structure of a naturally occurring human antibody that recognizes and disrupts a portion of the hemagglutinin (HA) protein that the virus uses to enter and infect cells.  The site was not expected to be vulnerable to such an antibody strike; the discovery could aid the quest for a universal flu vaccine.

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