Thursday, August 22, 2019 Newborn Screening Aids Discovery of Novel Gene Variants Credit: U.S. Air Force Variations in a single copy of a gene called FOXN1 can cause a positive newborn screening test for SCID, a life-threatening condition typically treated by bone marrow transplantation. Infants with FOXN1 haploinsufficiency, in which one of two FOXN1 copies harbors mutations that hamper its function, may have low T-cell levels at birth and thus be at increased risk for infections, a new study by NIAID scientists and colleagues has revealed. However, these infants do not have SCID and do not require or benefit from bone marrow transplantation. National Institute of Allergy and Infectious Diseases  |  National Institutes of Health Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page. You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact subscriberhelp.govdelivery.com. This service is provided to you at no charge by National Institute of Allergy and Infectious Diseases (NIAID). This email was sent to myhcistech.healthnews360@blogger.com using GovDelivery Communications Cloud on behalf of: National Institute of Allergy and Infectious Diseases · 5601 Fishers Lane · Bethesda, MD 20892 · 1-866-284-4107