Monday, December 30, 2019 Advanced Techniques Refine Diagnosis of Autoinflammatory Diseases, Identify Three New Conditions In people with autoinflammatory diseases, the innate immune system attacks the body, causing fevers, rashes and organ damage that can prove disabling and even fatal to children and adults. While a variety of genetic abnormalities can cause these rare inherited disorders, similar symptoms make precise diagnosis and treatment a challenge. In a report published online ahead of print today in the Journal of Clinical Investigation, NIH researchers used advanced techniques in genetics and immunology to refine the diagnosis in patients with autoinflammatory diseases. In doing so, they identified three new conditions with distinct clinical and immunological features; two of these diseases are caused by mutations in genes that were not previously associated with autoinflammatory diseases. National Institute of Allergy and Infectious Diseases  |  National Institutes of Health Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page. You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact Subscriber Help. This service is provided to you at no charge by National Institute of Allergy and Infectious Diseases (NIAID). This email was sent to myhcistech.healthnews360@blogger.com using GovDelivery Communications Cloud on behalf of: National Institute of Allergy and Infectious Diseases · 5601 Fishers Lane · Bethesda, MD 20892 · 1-866-284-4107