Monday, February 24, 2020

NIAID Now: Interferon “Fingerprint” Refines Diagnoses of Rare Autoinflammatory Diseases, Identifies Three New Conditions

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Monday, February 24, 2020

NIAID Now: Interferon "Fingerprint" Refines Diagnoses of Rare Autoinflammatory Diseases, Identifies Three New Conditions

Orange Autoinflammatory Disease Awareness Ribbon

Image: Orange autoinflammatory diseases awareness ribbon

Medicine has recognized rare autoinflammatory diseases for just over 20 years. While early diagnosis and treatment can improve patient outcomes, similar symptoms across different autoinflammatory diseases can make them difficult to diagnose and manage. Now, NIAID scientists and their colleagues have developed an integrated approach that combines next-generation genetic sequencing with advanced diagnostic techniques to characterize inflammatory responses. In doing so, investigators discovered three new autoinflammatory diseases. Their findings were published today in The Journal of Clinical Investigation.

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