Thursday, October 8, 2020

New Data Presented from Trial of Remdesivir Plus Baricitinib for COVID-19

The trial, ACTT-2, examined the safety and efficacy of a combination of remdesivir and baricitinib for hospitalized COVID-19 patients.
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Thursday, October 8, 2020

New Data Presented from Trial of Remdesivir Plus Baricitinib for COVID-19

ACTT-2 image

Today, John Beigel, M.D., associate director for clinical research in the Division of Microbiology and Infectious Diseases at NIAID, presented new data from a trial examining the safety and efficacy of a combination of remdesivir and baricitinib for hospitalized COVID-19 patients (ACTT-2). The presentation, which was given during the Special isirv-AVG Virtual Conference on Therapeutics for COVID-19, expanded on the primary results of the trial which were announced earlier this year, which indicated that the combination of remdesivir and baricitinib reduced time to recovery in hospitalized patients. Dr. Beigel noted that participants' condition at Day 15 of their participation in the trial was improved when they received the combination of the two therapeutics. Patients who required oxygen during their hospitalization appear to have received the largest benefit for the treatment. Investigators are completing their full analysis of the results, and a manuscript in a peer-reviewed publication will be available soon.



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