Monday, November 30, 2020

Experimental Vaccine for Crimean-Congo Hemorrhagic Fever

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Monday, November 30, 2020

Experimental Vaccine for Deadly Tickborne Virus Effective in Cynomolgus Macaques

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An experimental vaccine developed by NIAID scientists and European colleagues against Crimean-Congo hemorrhagic fever virus has protected cynomolgus macaques in a new study published in Nature Microbiology. The scientists used the DNA-based vaccine to prevent infection by CCHFV, a tickborne virus found in the Middle East, Asia, Africa and parts of Europe. The virus also can be transmitted to people by direct contact with infected fluids or tissue from people or certain livestock species. CCHFV infects up to 15,000 people annually, according to the World Health Organization. About 1 in 8 of those who are infected develop severe disease, which leads to about 500 deaths each year. CCHFV also is considered a possible agent of bioterrorism.

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