Wednesday, November 25, 2020 Microbiome-Driven Immune Cell Organization in the Liver Promotes Host Defense Immunofluorescence images showing distribution of immune cells (red) in liver cells surrounding the portal vein (blue) and endothelial cells (white). Credit: A. Gola and R.N. Germain, NIAID Research led by NIAID scientists has uncovered an unexpected spatial organization of immune cells in the liver that plays a critical role in protecting against blood-borne pathogens by preventing their spread throughout the body. Experiments with mouse models revealed that immune organization is established and sustained by interactions between the microbiome and liver endothelial cells. The NIAID researchers and their colleagues report the findings today in Nature. National Institute of Allergy and Infectious Diseases  |  National Institutes of Health Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page. You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact Subscriber Help. This service is provided to you at no charge by National Institute of Allergy and Infectious Diseases (NIAID).                             This email was sent to myhcistech.healthnews360@blogger.com using GovDelivery Communications Cloud on behalf of: National Institute of Allergy and Infectious Diseases · 5601 Fishers Lane · Bethesda, MD 20892 · 1-866-284-4107