Tuesday, November 3, 2020

New Cell Envelope Tethering Mechanism

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Tuesday, November 3, 2020

NIAID Scientists and Colleagues Reveal New Tethering Mechanism in a Gram-Negative Cell Envelope

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NIAID researchers and colleagues have discovered a mechanism that some bacteria, such as those that cause Q fever and Legionaries disease, use to assemble their cell envelope. Their study in Nature Microbiology explains how these pathogens use many different membrane proteins, called "porins," to tether the outer membrane to the bacterial cell wall. These findings offer a new perspective on bacterial cell structure, which is important for development of new antimicrobial therapies.

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