Tuesday, January 26, 2021

Antibody Infusions Prevent Acquisition of Some HIV Strains, NIH Studies Find

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Tuesday, January 26, 2021

Antibody Infusions Prevent Acquisition of Some HIV Strains, NIH Studies Find

Model of the VRC01 antibody

Model of VRC01, the anti-HIV broadly neutralizing antibody evaluated in the AMP Studies. Credit: NIAID

An investigational anti-HIV antibody delivered intravenously once every eight weeks safely and effectively prevented acquisition of HIV strains sensitive to that antibody, but did not significantly reduce overall HIV acquisition after 80 weeks among participants in two multinational clinical trials. Insights gleaned from these trials, known as the Antibody-Mediated Prevention (AMP) Studies, lay the foundation for future development of long-acting antibody-based HIV prevention tools and, ultimately, a vaccine. Results from the trials will be discussed during the 4th HIV Research for Prevention Conference (HIV R4P // Virtual).

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