Tuesday, January 5, 2021

Large Clinical Trial Will Test Combination Monoclonal Antibody Therapy for Mild/Moderate COVID-19

The ACTIV-2 trial has begun testing the safety and efficacy of BRII-196 and BRII-198.
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Tuesday, January 5, 2021

Large Clinical Trial Will Test Combination Monoclonal Antibody Therapy for Mild/Moderate COVID-19

ACTIV-2 image

A NIAID-sponsored clinical trial to evaluate a combination monoclonal antibody therapy for COVID-19 has begun to enroll people who have mild or moderate cases of the disease. The ACTIV-2 trial, which has previously tested the LY-CoV555 monoclonal antibody, has begun testing the safety and efficacy of BRII-196 and BRII-198, a pair of antibodies which are given together in IV infusions. Initially, the trial will enroll a small group of participants, and will then be expanded to enroll a larger group if a DSMB review indicates that that there are no serious safety concerns and the therapeutics may be effective.

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