Tuesday, January 5, 2021 A NIAID-sponsored clinical trial to evaluate a combination monoclonal antibody therapy for COVID-19 has begun to enroll people who have mild or moderate cases of the disease. The ACTIV-2 trial, which has previously tested the LY-CoV555 monoclonal antibody, has begun testing the safety and efficacy of BRII-196 and BRII-198, a pair of antibodies which are given together in IV infusions. Initially, the trial will enroll a small group of participants, and will then be expanded to enroll a larger group if a DSMB review indicates that that there are no serious safety concerns and the therapeutics may be effective. |
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