Monday, February 8, 2021 A NIAID-supported Phase 3 trial to test therapeutics for COVID-19 has begun enrolling participants in a new sub-study. New participants in the ACTIV-3 placebo-controlled trial may now be randomized to receive a long-acting antibody combination from AstraZeneca. The sub-study is running concurrently with two other studies of investigational monoclonal antibody therapies. The trial will initially enroll participants hospitalized with mild-to-moderate cases of COVID-19. If a therapeutic appears to be safe and effective after a DSMB has reviewed data from the first set of participants, the trial will expand to enroll more hospitalized participants, some of whom may have more severe cases of COVID-19. |
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