Thursday, April 22, 2021 A new clinical trial to test therapeutics in severely ill COVID-19 patients has begun enrolling participants. ACTIV-3 Critical Care is a master protocol designed to test multiple therapeutics at once. It will begin by testing Zyesami, an formulation of a synthetic vasoactive intestinal peptide which may have anti-inflammatory properties, and the antiviral remdesivir (Veklury). This placebo-controlled trial may reveal new treatment regimens for Acute Respiratory Distress Syndrome (ARDS), a life-threatening condition associated with SARS-CoV-2 infection. |
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