RFI: Inviting Comments/Suggestions on the Impact of Radiation Exposure on the Microbiome & the Development of Targeted Therapeutics

Leading Research to Understand, Treat, and Prevent Infectious, Immunologic, and Allergic Diseases          Visit us on the Web New Request for Information (RFI) Request for Information (RFI): Inviting Comments and Suggestions on the Impact of Radiation Exposure from a Radiological or Nuclear Incident on the Microbiome and the Development of Targeted Therapeutics (NOT-AI-21-055), National Institute of Allergy and Infectious Diseases (NIAID). This RFI is intended to solicit input from the radiation biology and microbiome research communities regarding the state of the science of the interplay between radiation exposure and the microbiome, including, but not limited to, the impact of radiation on the known microbiome niches in the human body (e.g., skin, oral mucosa, gastrointestinal [GI] tract, lungs), microbiome signatures that may predict susceptibility or resilience to radiation injury, and/or microbiota-based or microbiota-targeted radiation medical countermeasures (MCMs). NIAID, of the National Institutes of Health (NIH), will use the information obtained in response to this RFI to develop recommendations for future programs to support research and development of effective and safe radiation MCMs and/or identification of biomarkers and biodosimetry tools targeting/using the microbiome. Release date: May 21, 2021 Response date: August 15, 2021 NIAID is looking for information on: The microbiome in the various organ tissues of the body, and their involvement in radiation pathogenesis in those tissues and organs affected by total and/or partial body radiation exposure. Studies of radiation effects on the microbiome in animal models. Identification and demonstration of efficacy of MCM candidates targeting the microbiome or the immune system's interaction with the microbiome. RFI responses should be directed to Andrea DiCarlo, Ph.D., NIAID Division of Allergy, Immunology and Transplantation (DAIT), Radiation and Nuclear Countermeasures Program (RNCP) via email at cohena@niaid.nih.gov. Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page. You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact subscriberhelp.govdelivery.com. This service is provided to you at no charge by National Institute of Allergy and Infectious Diseases (NIAID). This email was sent to myhcistech.healthnews360@blogger.com using GovDelivery Communications Cloud on behalf of: National Institute of Allergy and Infectious Diseases · 5601 Fishers Lane · Bethesda, MD 20892 · 1-866-284-4107