Friday, July 16, 2021

NIAID Research Informs Guideline for Treating People with ANCA-Associated Vasculitis

Study found that giving rituximab once weekly for a month provided the same benefits as 18 months of daily immunosuppressive therapy.
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Friday, July 16, 2021

NIAID Research Informs Guideline for Treating People with ANCA-Associated Vasculitis

Image of retinal blood vessels

Projected image (focus stacked) of the vascular branches in the retina at the back of the eye. Credit: Bryan William Jones

A NIAID-funded study contributes to the evidence for a new guideline on how to induce remission and treat relapse of a rare, severe autoimmune disease called ANCA-associated vasculitis. The study found in 2013 that giving the drug rituximab to people with ANCA-associated vasculitis once weekly for a month provided the same benefits as 18 months of daily immunosuppressive therapy. The new guideline recommends that doctors use rituximab as a first-line drug to induce and maintain remission of active, severe ANCA-associated vasculitis.

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