Testing Novobiocin in PARP Inhibitor-Resistant Cancers - Cancer Currents Blog

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You are subscribed to Cancer Currents: An NCI Cancer Research Blog from the National Cancer Institute. Recent posts are listed below.     Can an Antibiotic Treat Cancers that Become Resistant to PARP Inhibitors? 07/27/2021 In lab studies, the antibiotic novobiocin showed promise as a treatment for cancers that have become resistant to PARP inhibitors. The drug, which inhibits a protein called DNA polymerase theta, will be tested in NCI-supported clinical trials.

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