| Join a study evaluating rapid and sustained antidepressant effects of repeated doses of ketamine. This 14 - to 20 -week inpatient study is enrolling eligible depressed adults, ages 18 to 65, who are free of other serious medical conditions. Procedures include 10 infusions of low-dose ketamine (an FDA-approved anesthetic), two infusions of placebo, brain scans, EEG, transcranial magnetic stimulation (TMS), and psychological evaluations. The study is conducted at the NIH Clinical Center in Bethesda, MD. There is no cost to participate and compensation is provided. This study enrolls eligible participants from across the USA. Travel arrangements are provided and costs are covered by NIMH (arrangements vary by distance). 1-877-646-3644 (TTY: 1-866-411-1010) or email: moodresearch@mail.nih.gov Department of Health & Human Services, National Institutes of Health, National Institute of Mental Health, Protocol #17-M-0060 | 
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