Monday, October 18, 2021

Interferon Does Not Improve Outcomes for Hospitalized Adults with COVID-19

Trial tested interferon beta-1a plus remdesivir versus remdesivir alone.
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Monday, October 18, 2021

Interferon Does Not Improve Outcomes for Hospitalized Adults with COVID-19

Colorized scanning electron micrograph of a human cell infected with SARS-CoV-2 virus particles

A NIAID clinical trial has found that treatment with the immunomodulator interferon beta-1a plus the antiviral remdesivir was not superior to treatment with remdesivir alone in hospitalized adults with COVID-19 pneumonia. In addition, in a subgroup of patients who required high-flow oxygen, investigators found that interferon beta-1a was associated with more adverse events and worse outcomes. These findings were published today in the journal The Lancet Respiratory Medicine.

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