Wednesday, November 24, 2021

Oral Probiotic Bacillus Prevents Enterococcal Sepsis in Mouse Study

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Wednesday, Nov. 24, 2021

Oral Probiotic Bacillus Prevents Enterococcal Sepsis in Mouse Study

NIAID intramural scientists have shared an unexpected finding in their continuing study of a common probiotic digestive supplement, Bacillus bacteria, as a treatment for bacterial gut infections. Bacillus given orally stopped colonizing pathogenic Enterococcus faecalis from spreading into the bloodstream and causing a system-wide infection known as sepsis. The study, published in Science Translational Medicine, builds on research from 2018 where the same group discovered that people with Bacillus in their gut never were colonized with a different bacterium, Staphylococcus aureus, which has a similar sensing mechanism as E. faecalis.

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