Thursday, January 27, 2022

COVID-19 Treatment News: hIVIG does not improve outcomes for adults hospitalized with COVID-19

Trial compared hIVIG plus remdesivir to remdesivir alone
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Thursday, January 27, 2022

Hyperimmune intravenous immunoglobulin does not improve outcomes for adults hospitalized with COVID-19

SEM image of SARS-CoV-2 particles emerging from infected cell

Scanning electron microscope image of SARS-CoV-2 (round gold particles) emerging from the surface of a cell cultured in the lab. Image captured and colorized at Rocky Mountain Laboratories in Hamilton, Montana. Credit: NIAID

A NIAID-funded clinical trial has found that the combination of remdesivir plus a highly concentrated solution of antibodies that neutralize SARS-CoV-2, the virus that causes COVID-19, is not more effective than remdesivir alone for treating adults hospitalized with the disease. The trial also found that the safety of this experimental treatment may vary depending on whether a person naturally generates SARS-CoV-2-neutralizing antibodies before receiving it. The results of the multinational Phase 3 trial were published today in the journal The Lancet.

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