Friday, April 1, 2022

Alzheimer's-Linked Protein May Help Melanoma Spread to Brain | FDA Approval for Prostate Cancer - Cancer Currents Blog

National Cancer Institute

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04/01/2022
Melanoma cells that travel to the brain produce their own amyloid beta, helping the cells survive and form metastases, a new study in mice shows. The Alzheimer's-linked proteins appear to tamp down the brain's immune response to the cancer cells.
An update has been made to a June 2021 Cancer Currents story on a clinical trial of 177Lu-PSMA-617, a type of drug known as a radiopharmaceutical, in men with advanced prostate cancer. On March 23, the Food and Drug Administration approved 177Lu-PSMA-617, which will be marketed as Pluvicto, based on the results of that clinical trial.
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