Wednesday, July 6, 2022

New Coronavirus Vaccine Study Shows Potential for ‘Mosaic’ Design

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Wednesday, July 6, 2022

New Coronavirus Vaccine Study Shows Potential for 'Mosaic' Design

mosaic vax

Caption: This scanning electron microscope image shows SARS-CoV-2 (round gold objects) emerging from the surface of cells cultured in the lab. (NIAID)

 

NIAID scientists and colleagues have developed a promising pan-coronavirus vaccine, according to a new study in Science. The candidate vaccine – called mosaic-8 – combines parts of eight different sarbecoviruses and generates a protective antibody response in mice and monkeys. The sarbecovirus subgenus includes coronaviruses such as SARS-CoV and SARS-CoV-2. In the study, mosaic-8 protected mice and monkeys against SARS-CoV-2 and SARS-CoV, which was not included in the vaccine. The scientists believe this type of vaccine design could protect against a target virus – like SARS-CoV-2 – as well as its variants and other related emerging coronaviruses.

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