Targeted Therapy for Glioma | Treatment for HER2-Low Breast Cancer | Menthol Cigarettes, Cancer Information Highlights, 07/06/2022

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Cancer Information Highlights From the National Cancer Institute Updating you about cancer causes, prevention, screening, treatment, coping, and more   New from NCI For Some Kids with Glioma, Targeted Therapy Is Better than Chemo   In a recent study, the combination of dabrafenib (Tafinlar) and trametinib (Mekinist) shrank more glioma tumors, kept the tumors at bay for longer, and caused fewer side effects than chemotherapy. The children all had glioma with a genetic mutation known as BRAF V600 in their cancer cells. Targeted Therapy Improves Survival for Metastatic "HER2-Low" Breast Cancer   People with metastatic breast cancer whose tumors had low levels of HER2 protein lived longer after treatment with trastuzumab deruxtecan (Enhertu) than those treated with standard chemotherapy. These findings could help about half of all people with metastatic breast cancer. FDA Proposes Rule Prohibiting Menthol Cigarettes A proposed rule prohibiting menthol flavoring is expected to make cigarettes less appealing, lower smoking rates, and reduce diseases and deaths caused by cigarette smoking. Tobacco control researchers say the proposed ban could have the greatest impact on youth and African American smokers. Use of Active Surveillance for Low-Risk Prostate Cancer Continues to Rise More people with low-risk prostate cancer are opting for active surveillance instead of having treatment right away. In fact, rates of active surveillance more than doubled between 2014 and 2021. PDQ Updates Acupuncture Acupuncture involves stimulating certain points on the body to promote health, or to lessen disease symptoms and treatment side effects. Learn more about acupuncture and its use in people with cancer. FDA Approvals Dabrafenib and Trametinib Approved for Certain Solid Tumors We've updated our drug summaries on dabrafenib (Tafinlar) and trametinib (Mekinist). The Food and Drug Administration approved these drugs to be used together to treat adults and children aged 6 years and older with solid tumors that have a BRAF mutation, have spread to other parts of the body or cannot be removed by surgery, have gotten worse after other treatment, and cannot be treated with other therapies.   Also of Interest List of Targeted Therapy Drugs Approved for Specific Types of Cancer Interested in learning more about targeted therapy drugs that have been approved to treat your cancer? This page lists drugs according to cancer type. Contact Us for Help Information specialists at NCI's Cancer Information Service (CIS), NCI's contact center, are available to help answer your cancer-related questions in English and Spanish. Reach us by phone, chat, or email.

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