Wednesday, December 20, 2023

Biomedical STI Prevention Evidence Is Inadequate for Cisgender Women

NIH leadership calls for population-specific considerations in study design.
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Wednesday, December 20, 2023

Biomedical STI Prevention Evidence Is Inadequate for Cisgender Women

Closely clustered spheres with irregular surfaces, with long thin strands between them.

Scanning electron micrograph of Neisseria gonorrhoeae bacteria, which causes gonorrhea. Captured by the Research Technologies Branch at the NIAID Rocky Mountain Laboratories in Hamilton, Montana. Credit: NIAID

Biomedical STI prevention evidence is inadequate for cisgender women. A study found doxycycline post-exposure prophylaxis (better known as DoxyPEP) did not prevent STI acquisition in cisgender women, despite showing promising results in gay, bisexual, and other men who have sex with men and transgender women in a previous study. NIAID Director Jeanne Marrazzo discusses evidence gaps and opportunities to correct them in an editorial published today in The New England Journal of Medicine.

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