Wednesday, February 21, 2024

Novel CMV Vaccine Generates Stronger Response in Key Immune Cells Than Previous Candidate

A vaccine designed to prevent human cytomegalovirus elicited long-lasting immune responses.
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Wednesday, February 21, 2024

Novel CMV Vaccine Generates Stronger Response in Key Immune Cells Than Previous Candidate

Multiple burgundy spheres on a light green background with dark green markings throughout.

Transmission electron micrograph of cytomegalovirus particles (burgundy) found within intracellular vesicles of an infected macrophage (green). Image captured at the NIAID Integrated Research Facility in Fort Detrick, Maryland.

Credit: NIAID

A messenger RNA (mRNA) vaccine designed to prevent human cytomegalovirus (CMV) elicited long-lasting CMV-specific responses from several types of immune cells, outperforming a previous vaccine concept in multiple measures in a NIAID-supported laboratory study. The findings were published in the Journal of Infectious Diseases.

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