Thursday, April 11, 2024

Androgens Control Skin Immunity in Mice, NIAID Researchers Find

Male mice have weaker immune responses in the skin than female mice.
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Thursday, April 11, 2024

Androgens Control Skin Immunity in Mice, NIAID Researchers Find

Black circle surrounded by sketchy red halo on background of purple, black and green.

Confocal microscopy image of dendritic cells (red) reaching into a hair follicle (black) in mouse skin. Credit: NIAID

Male mice have weaker immune responses to infection and microbial colonization of the skin than female mice because male sex hormones reduce the density and activation of key immune cells in skin, NIAID researchers have found. The findings are published in the journal Science.

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