Friday, May 3, 2024

Making an Impact: Results from an NIAID-funded Study of Hospitalized COVID-19 Patients

Two recent publications explore why some people hospitalized with COVID-19 fare better than others.
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Friday, May 3, 2024

Making an Impact: Results from an NIAID-funded Study of Hospitalized COVID-19 Patients

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Why do some people hospitalized with COVID-19 succumb, while others—with apparently similar disease severity at the time of hospitalization—survive? Among older individuals, are there particular immune responses to SARS-CoV-2 virus infection that set the stage for the increased risk of severe COVID-19? These are among the questions addressed in the NIAID-funded Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study. Two recent publications by IMPACC network investigators provide a detailed picture of the immunologic dynamics of COVID-19 disease in a large cohort of patients who were hospitalized prior to the wide-spread availability of COVID vaccines.

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