Immunology News: Researchers Find Small Molecules That Trigger Trained Immunity

The compounds surprisingly include steroids, which are usually immunosuppressive.

Thursday, July 25, 2024 Researchers Find Small Molecules That Trigger Trained Immunity Model of flunisolide, a steroid drug and one of the most promising compounds identified in the study. Credit: PubChem. Recolored by NIAID. NIAID-supported scientists have identified small molecules that trigger trained immunity, a form of innate immune-system memory, without a pathogen or host molecule activating innate immunity first. These newly identified compounds surprisingly include steroids, which are usually immunosuppressive. Also, unlike the few previously identified molecules that trigger trained immunity, the new ones are easy to make and deliver, the scientists say. These findings could help researchers develop new or improved vaccines and treatments. National Institute of Allergy and Infectious Diseases  |  National Institutes of Health Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page. You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact Subscriber Help. Your subscription may be removed if you do not open our emails for a six-month period.  This service is provided to you at no charge by National Institute of Allergy and Infectious Diseases (NIAID).                             This email was sent to myhcistech.healthnews360@blogger.com using GovDelivery Communications Cloud on behalf of: National Institute of Allergy and Infectious Diseases · 5601 Fishers Lane · Bethesda, MD 20892 · 1-866-284-4107