Friday, October 25, 2024

Can Improved Tests Speed Up Treatment for Antibacterial Resistant Infections?

An ongoing NIAID-supported trial is testing whether rapid tests for antibiotic susceptibility can improve patient outcomes.
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Friday, October 25, 2024

Can Improved Tests Speed Up Treatment for Antibacterial Resistant Infections?

Klebsiella

A human neutrophil interacting with Klebsiella pneumoniae (pink), a multidrug–resistant bacterium that causes severe hospital infections. Credit: NIAID

Recently, the UN General Assembly high-level meeting on antimicrobial resistance highlighted the ongoing need for decisive action on the growing threat posed by pathogens that are gaining resistance to common treatments. For many patients with antibiotic-resistant infections, finding an antibiotic that will successfully fight the infection can take hours or days of testing—and, researchers suspect, those days may mean the difference in how well the patient recovers. A trial from the NIAID-supported Antibacterial Research Leadership Group (ARLG) is investigating whether a rapid test of antibiotic susceptibility for bacteria growing in blood cultures improves clinical outcomes for patients with sepsis in settings that have high rates of antibiotic-resistant bacterial infections.

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