Wednesday, January 15, 2025

Subclinical Disease in Monkeys Exposed to H5N1 by Mouth and Stomach

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Wednesday, Jan. 15, 2025

Subclinical Disease in Monkeys Exposed to H5N1 by Mouth and Stomach

H5N1 flu milk

Colorized transmission electron micrograph of avian influenza A H5N1 virus particles (yellow), grown in epithelial cells. Microscopy by CDC; repositioned and recolored by NIAID. Credit: CDC and NIAID

A new NIAID study published in Nature found that highly pathogenic H5N1 avian influenza virus (HPAI H5N1) administered directly into the mouth and stomach of research monkeys caused self-limiting infection with no disease signs. By comparison, other routes of transmission resulted in mild or severe disease. The findings suggest that drinking raw milk contaminated with H5N1 virus can result in infection but may be less likely to lead to severe illness. Nevertheless, exposure by raw milk should be avoided to prevent H5N1 infection and potential further spread.

 

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