Wednesday, January 13, 2021

NIAID Scientists Study Salmonella Swimming Behavior as Clues to Infection

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Wednesday, January 13, 2021

NIAID Scientists Study Salmonella Swimming Behavior as Clues to Infection

Salmonella

NIAID scientists and their colleagues believe they have identified a Salmonella Typhimurium protein that allows the bacteria to swim straight, rather than rotating, when they are ready to infect cells. This new study, in Nature Communications, describes S. Typhimurium movement and shows that the protein is required for the bacteria to invade surface epithelial cells in the gut. The study authors suggest that the protein is a potential target for developing new antibacterial treatments to hinder the bacteria from infecting cells and colonizing the gut. S. Typhimurium commonly cause human gastroenteritis, inflammation of the lining of the intestines.

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