Thursday, August 11, 2022

Asthma News: Monoclonal Antibody Reduces Asthma Attacks in Urban Youth

Mepolizumab decreased asthma attacks by 27% in Black and Hispanic children and adolescents.
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Thursday, August 11, 2022

Monoclonal Antibody Reduces Asthma Attacks in Urban Youth

Illustration of child in urban setting holding asthma inhaler

Illustration of a child using an asthma inhaler in an urban setting. Cells called eosinophils, present at high levels in the blood and airways of many people with untreated asthma, appear in the lower third of the illustration. Credit: NIAID

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a NIAID clinical trial has found. This population has been underrepresented in previous clinical trials of asthma therapeutics. The findings were published today in the journal The Lancet.

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