Thursday, January 5, 2023

Autoimmune Disease News: Newly Discovered Species of Gut Bacteria May Cause Some Cases of Rheumatoid Arthritis

Immune-system targets shared by the bacterium and joint tissue may have a similar structure or amino-acid sequence.
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Thursday, January 5, 2023

Newly Discovered Species of Gut Bacteria May Cause Some Cases of Rheumatoid Arthritis

Photo of a hand affected by rheumatoid arthritis

A hand disfigured by rheumatoid arthritis. Credit: James Heilman, M.D. Image licensed under CC BY-NC-SA 2.0.

Research by NIAID grantees strongly suggests that immune responses to a newly discovered species of gut bacteria may cause some cases of rheumatoid arthritis, or RA, a common autoimmune disease. RA may develop because immune-system targets shared by this bacterium and joint tissue have a similar structure or amino-acid sequence. The findings were recently published in Science Translational Medicine.

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