Thursday, November 30, 2023

Antibodies Passed through Placenta May Improve Survival for Infants with HIV

Certain antibodies that pass through the placenta are associated with improved survival of infants who acquire HIV through nursing.
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Thursday, Nov. 30, 2023

Antibodies Passed through Placenta May Improve Survival for Infants with HIV

Black and dark blue granulated wavy matter with two light yellow spheres budding off to the right.

Caption: Colorized transmission electron micrograph of two HIV-1 virus particles (yellow) budding from the plasma membrane of an infected H9 T cell (blue). Image captured at the NIAID Integrated Research Facility in Fort Detrick, Maryland. (Credit: NIAID)

A Kenya-based study found certain antibodies that pass through the placenta are associated with the improved survival of infants who acquire HIV through nursing. The study observed that preexisting antibodies that target a region of a protein on HIV's surface were correlated with delayed HIV acquisition in infants exposed to the virus as well as a lower amount of virus circulating in the blood of infants who acquired HIV.

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