Scientists Identify Cellular, Tissue Features in Early Relapsing Follicular Lymphoma

Findings could help predict early relapse among people with follicular lymphoma.

Wednesday, March 5, 2024 NIAID & NCI Scientists Identify Cellular, Tissue Features in Early Relapsing Follicular Lymphoma IBEX imaging of biopsies from normal and malignant lymph nodes shows the changes in cells and tissue architecture arising from follicular lymphoma. Normal and tumor B cells are aqua, follicular dendritic cells are yellow, T cells are magenta, and CD4+ T cells and macrophages are blue. Credit: NIAID Scientists at NIAID and the National Cancer Institute have prospectively identified distinguishing features and patterns in the tumors and lymph-node tissue of people with follicular lymphoma who relapsed within 24 months of initial treatment compared with those who did not. These findings could help clinicians predict early relapse among people with follicular lymphoma and inform treatment decisions. The scientists conducted the research in part with technology they created—an imaging system called IBEX—that enabled a fine-grained analysis of lymph-node cells in the context of their tissue microenvironment. The findings are published in the journal Cancer Cell. National Institute of Allergy and Infectious Diseases  |  National Institutes of Health Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page. You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact Subscriber Help. This service is provided to you at no charge by National Institute of Allergy and Infectious Diseases (NIAID).                             This email was sent to myhcistech.healthnews360@blogger.com using GovDelivery Communications Cloud on behalf of: National Institute of Allergy and Infectious Diseases · 5601 Fishers Lane · Bethesda, MD 20892 · 1-866-284-4107