Tuesday, March 5, 2024

Vaginal Ring and Oral Pre-Exposure Prophylaxis Found Safe for HIV Prevention Throughout Pregnancy

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Tuesday, March 5, 2024

Vaginal Ring and Oral Pre-Exposure Prophylaxis Found Safe for HIV Prevention Throughout Pregnancy

Dapivirine CROI

Transmission electron micrograph of HIV-1 virus particles (pink) replicating from the plasma membrane of an H9 T cell. Image captured at the NIAID Integrated Research Facility in Fort Detrick, Maryland. Credit: NIAID

Pregnant people are three times more likely to acquire HIV than those who are not pregnant. A NIAID-sponsored study presented at the 2024 Conference on Retroviruses and Opportunistic Infections showed that the dapivirine vaginal ring or oral PrEP was safe for HIV prevention throughout pregnancy. The large clinical study was conducted in South Africa, Uganda and Zimbabwe by the NIH-funded Microbicide Trials Network.

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